Treatment options are based on the type of lung cancer you have, as well as the size and stage of the lung cancer. This means that small-cell lung cancer is treated differently from NSCLC. Once your oncologist has determined the lung cancer’s profile, they will present you with a personalized treatment plan. Several different treatments may be used in a single plan.
Chemotherapy is often the primary treatment for small cell lung cancer. SCLC tends to spread throughout the body rather quickly, which means it is usually spread past the lungs by the time it is discovered. Chemo is given because it reaches cancer cells throughout the body.
Chemotherapy uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy). When chemotherapy is placed directly into the spinal column, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas (regional chemotherapy). The way the chemotherapy is given depends on the type and stage of the lung cancer being treated.
For people with limited-stage small cell lung cancer, chemotherapy is usually given with radiation in a treatment called chemoradiation. However, for people with extensive-stage small cell lung cancer, chemotherapy with or without immunotherapy may be given.
Radiation therapy is a cancer treatment that uses high-energy X-rays or other types of radiation to kill cancer cells or keep them from growing.
There are two types of radiation therapy:
The way the radiation therapy is given depends on the type and stage of the lung cancer being treated.
A more recent approach to delivering radiotherapy is called hypofractionated radiation therapy, where the same overall dose of radiation is given in a shorter time period. Instead of getting radiation therapy for 6-8 weeks, the same results can be achieved in 4-5 weeks by giving a higher dose of radiation at each treatment. The shorter radiation treatments are made possible through advanced technology that precisely aims radiation, allowing the cancerous cells to be treated with a higher dose while sparing nearby organs and tissues. The final number of treatments depends on the specific cancer diagnosis.
Radiation therapy may be used for small-cell lung cancer in the following ways:
Surgery may be used if the cancer is found in one lung and in nearby lymph nodes only. Because this type of lung cancer is usually found in both lungs, surgery alone is not often used to treat SCLC.
If your doctor believes you may be a good candidate for surgery, then the following will take place:
Even if the doctor removes all cancer that can be seen at the time of the operation, some patients may be given chemotherapy or radiation therapy after surgery to kill any cancer cells that are left. Treatment given after the surgery to lower the risk that your lung cancer will come back is called adjuvant therapy.
Immunotherapy is essentially a cancer treatment that uses your own immune system to help fight cancer. Substances produced by your body or made in a laboratory are used to jumpstart your body’s natural defense against disease.
Lung cancer immunotherapy belongs to a class called checkpoint inhibitors. These “checkpoints” — proteins on immune cells that need to be turned on (or off) to start an immune response — are what the immune system uses to keep itself from attacking your normal cells. Cancer cells sometimes use these checkpoints to avoid being attacked by the immune system. However, drugs that target these checkpoints can be used in the treatment plan for people with advanced small-cell lung cancer, and this is called immune checkpoint inhibitor therapy.
The following types of immunotherapy may be used for SCLC:
An endoscope is a thin, tube-like instrument used to look at tissues inside the body. An endoscope has a light and a lens for viewing and may be used to place a stent in a body structure to keep the structure open. Endoscopic stent placement can be used to open an airway blocked by abnormal tissue.
Laser therapy is a cancer treatment that uses a laser beam (a narrow beam of intense light) to kill cancer cells. It is often used alongside other forms of small-cell lung cancer treatment. It is sometimes used when a tumor is blocking off the airway and making it difficult for you to breathe properly.
Some lung cancer treatments are currently used treatments, but there are others being tested in clinical trials.
A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with cancer. When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment. Patients may want to think about taking part in a clinical trial. Some clinical trials are open only to patients who have not started treatment, but the cancer care team at Willamette Valley Cancer Institute can help you determine if you are an ideal candidate for a clinical trial.
If you have been newly diagnosed with lung cancer, the first step is to schedule a consultation with a lung cancer specialist at WVCI. We offer personalized treatment plans, including the latest cancer treatments available, as well as second opinions on treatment in Albany, Corvallis, Eugene, Florence, Lincoln City, and Newport, Oregon.