Myelodysplastic syndromes are a group of diseases caused by the inadequate production of healthy blood cells in the bone marrow. They are diseases of the blood and bone marrow.
Normally, the bone marrow makes blood stem cells (immature cells) that develop into mature blood cells over time. A blood stem cell may become a myeloid stem cell or a lymphoid stem cell. The lymphoid stem cell develops into a white blood cell. The myeloid stem cell develops into one of three types of mature blood cells:
Continue reading below to learn more about myelodysplastic syndromes, including:
There are several types of myelodysplastic syndromes, all of which are characterized by too few of one or more types of healthy blood cells in the bone marrow or blood.
Tests that examine the blood and bone marrow are used to detect (find) and diagnose myelodysplastic syndromes. The following tests and procedures may be used.
There is no staging system for myelodysplastic syndromes. Treatment is based on whether the disease developed after the patient was exposed to factors that cause myelodysplastic syndrome or the disease was previously treated. Myelodysplastic syndromes are grouped for treatment as follows:
Treatment of de novo and secondary myelodysplastic syndromes may include the following:
Treatment of previously treated myelodysplastic syndromes may include the following: